Researchers at the University of East Anglia say they’ve developed the world’s first reliable blood test for chronic fatigue syndrome (ME/CFS).
The condition, marked by extreme and unexplained exhaustion, has long lacked a diagnostic test, leaving many patients undiagnosed or misdiagnosed.
“This is a significant step forward,” said Prof Dmitry Pshezhetskiy. “For the first time, we can reliably identify ME/CFS.”
The test, developed with Oxford Biodynamics, analyses how DNA folds in blood cells to detect a unique pattern seen only in ME/CFS patients.
In trials involving 47 patients and 61 healthy adults, the test showed 92% sensitivity and 98% specificity.
“It could transform diagnosis and management,” Pshezhetskiy said.
However, experts urged caution. Dr Charles Shepherd of the ME Association called the findings “important but early,” stressing the need for wider testing.
Prof Chris Ponting warned the claims were “premature,” adding that validation through independent studies is essential before clinical use.
